This invention concerns HIV replication inhibitors of formula ##STR00001## the N-oxides, the pharmaceutically acceptable addition salts, the quaternary amines and the stereochemically isomeric forms thereof, provided that when Q is halo then Z is N; or when Q is polyhaloC.sub.1-6alkyl then Y is hydrogen or C.sub.1-6alkyl; their use as a medicine, their processes for preparation and pharmaceutical compositions comprising them.