A patient monitoring system is disclosed. The patient monitoring system includes at least one monitoring cable, a plurality of connecting wires, and a plurality of connectors. The plurality of connecting wires are housed within an outer covering and each extend from a first end to a second end of the at least one monitoring cable. The plurality of connectors are arranged in an in-line sequence from the first end to the second end of the at least one monitoring cable and may include at least one ECG connector and at least one non-ECG connector. The patient monitoring system may also be configured to provide strain relief for the at least one cable.