A compound of formula (I): in which A is a C alkylene group with a chain
length between NH and N(O)R'R'' of at least 2 carbon atoms and R' and R''
are each separately selected from C.sub.1-4 alkyl groups and C.sub.2-4
hydroxyalkyl and C.sub.2-4 dihydroxyalkyl groups, or R' and R'' together
are a C.sub.2-6 alkylene group, is formulated so that upon dissolution in
aqueous solution the pH of the solution is in the range of 5 to 9. The
compound may be in the form of salt with a physiologically acceptable
acid having a pK.sub.a in the range of -3.0 (minus 3.0) to 9.0
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