The invention relates to compounds of formula (I) B-Q-X.sub.1, wherein B
is a bioactive, cell adhesive mediating molecule, selected from the group
(i) and Thr-Trp-Tyr-Lys-Ile-Ala-Phe-Gln-Arg-Asn-Arg-Lys (SEQ ID NO: 1)
(ii), Trp-Tyr-Lys-Ile-Ala-Phe-Gln-Arg-Asn-Arg-Lys (SEQ ID NO: 2) (iii),
Tyr-Lys-Ile-Ala-Phe-Gln-Arg-Asn-Arg-Lys (SEQ ID NO: 3) (iv),
Thr-Trp-Tyr-Lys-Ile-Ala-Phe-Gln-Arg-Asn-Arg (SEQ ID NO: 4) (v),
Thr-Trp-Tyr-Lys-Ile-Ala-Phe-Gln-Arg-Asn (SEQ ID NO: 5) (vi),
Thr-Trp-Tyr-Lys-Ile-Ala-Phe-Gln-Arg (SEQ ID NO: 6) (vii), wherein (i) X,
Y, Z, R.sup.2, R.sup.3, R.sup.4, A, Ar, Hal, Het, Het.sup.1, n, m, o, p,
q, s, t have the meanings cited in claim 1, Q is absent or is an organic
spacer molecule, X.sub.1 is an anchor molecule selected from the group
cited in claim 1, and the salts thereof, which can be used as integrin
inhibitors particularly for treatment of illness, deficiencies and
inflammations caused by implants and osteolytic illnesses such as
osteoporosis, thrombosis, cardiac infarction and arteriosclerosis, in
addition to the acceleration and strengthening of the integration process
of implants or the biocompatible surface in tissue.