A nucleic acid molecule or construct alone or with a promoter suitable for
expression control is contemplated that codes for a KLH1 haemocyanin, a
haemocyanin domain or a fragment thereof with the immunological
properties of at least one domain of haemocyanin, and comprises at least
one intron sequence, as well as haemocyanin fusion proteins. The
construct can also comprise a nucleic acid sequence that codes for an
antigen. Host cells are also contemplated that contain the nucleic acid
molecule or construct and a recombinant expression product thereof. The
invention further relates to a pharmaceutical composition that comprises
the expression product and antibodies obtainable by immunization of an
animal therewith, as well as the use of antibodies in screening methods
for the identification of tumors.