A stable continuous method for producing ethanol from the anaerobic
bacterial fermentation of a gaseous substrate containing at least one
reducing gas involves culturing a fermentation bioreactor anaerobic,
acetogenic bacteria in a liquid nutrient medium; supplying the gaseous
substrate to the bioreactor; and manipulating the bacteria in the
bioreactor by reducing the redox potential, or increasing the NAD(P)H TO
NAD(P) ratio, in the fermentation broth after the bacteria achieves a
steady state and stable cell concentration in the bioreactor. The free
acetic acid concentration in the bioreactor is maintained at less than 5
g/L free acid. This method allows ethanol to be produced in the
fermentation broth in the bioreactor at a productivity greater than 10
g/L per day. Both ethanol and acetate are produced in a ratio of ethanol
to acetate ranging from 1:1 to 20:1.