The present invention relates to a diagnostic X-ray device, system or apparatus for performing diagnostic radiology and a method of configuring such a diagnostic X-ray device, system or apparatus. More specifically, the present invention relates to a diagnostic system for forming at least one image of an object having enhanced contrast. The system comprises a beam source adapted to produce an imaging beam and a masking member adapted to form at least one beam portion from the imaging beam and adapted to image the object. The system further comprises a flat panel detector positioned in a path of at least one beam portion penetrating the object and adapted to form at least one image of the object.