An improved mechanism for routing communication traffic between a radio access network and distributed antenna system (DAS) remote antenna units. In accordance with an exemplary embodiment of the invention, a DAS hub and each DAS antenna unit served by the DAS hub will sit as a respective node on a packet-switched network. Further, the DAS hub will maintain or otherwise have access to a set of mapping data that correlates one or more radio access network coverage segments (e.g., cell sectors) with one or more DAS antenna unit addresses on the packet-switched network (e.g., IP addresses). Advantageously, an administrator of the DAS can then configure or alter the mapping data whenever desired, to conveniently set the RAN-DAS correlations and to thereby distribute RAN coverage in a desired manner throughout the DAS.