A method and apparatus for digital predistortion of power amplifiers are disclosed. Successful digital predistortion parameter settings are correlated with the operating conditions that affect the distortion of an amplifier. These operating conditions may include input power level, carrier frequency, temperature, DC supply voltage, or others. The successful predistortion parameter settings along with the corresponding operating conditions are stored in a list that is indexed using multi-dimensional attribute vectors. The elements of the list are generated automatically.