A cutting balloon catheter and method of making and using the same. The cutting balloon catheter may include a catheter shaft having a balloon coupled thereto. One or more cutting members or blades may be coupled to the balloon. The cutting members may include two or more sections that are connected via a fracturable or yielding bridge section that increases flexibility when passing through or being utilized in tortuous anatomy.

 
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> Compositions and methods for promoting internalization and degradation of urokinase-type plasminogen activator

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