The invention relates to the therapeutic or prophylactic treatment of
fungal infections. The invention provides new methods for therapeutically
or prophylactically treating fungal infections using sub-lethal
concentrations of an anti-invasin compound. The methods according to the
invention have fewer toxicology problems than existing methods, and thus
can be used prophylactically, as well as for early treatment for high
risk patients without a firm diagnosis. The methods according to the
invention can also be used to treat an established fungal infection. The
invention further provides novel genes that regulate fungal hyphal
growth.