The present invention provides pharmaceutical preparations for
anti-inflammation, anti-infection, inhibition of cancer metastasis etc.,
foods such as dairy products etc., and a method for improving proteins,
as well as a method for diagnosis of inflammatory diseases and cancer
malignancy. According to the present invention, there can be provided a
polypeptide having poly-N-acetyllactosamine sugar chains
synthesis-related activity, a process for producing the polypeptide, DNA
coding for the polypeptide, a process for producing the DNA, a
recombinant vector having the DNA integrated therein, a transformant
carrying the recombinant vector, an antibody recognizing the polypeptide,
a process for producing poly-N-acetyllactosamine sugar chains by use of
the DNA or the polypeptide, diagnosis and treatment of diseases such as
inflammations, cancers etc. by use of the DNA, the polypeptide or the
antibody, determination and immunostaining of the polypeptide of the
present invention by use of the antibody, a method for screening a
compound varying the expression of a gene coding for the polypeptide, and
a method for screening a substance varying the activity of the
polypeptide.