The present invention provides an improved preparation based on the
synergistic action of garlic extract and essential oil of M. spicata var.
Ganga or cinnamon oil against dermatophytic fungus. More particularly,
the present invention relates to the synergistic enhancement of activity
of a combination by menthyl acetate or Geraniol. The invention also
provides a method of preparation of the synergistic combination and the
shelf life observed to be more than one year. The cream based preparation
is a potent anti-dermatophytic as described and illustrated by in vitro
and in vivo evaluations.