Progesterone receptor modulators of formula I, or a pharmaceutically acceptable salt thereof, ##STR00001## wherein R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, R.sub.6 and R.sub.7 are as defined herein, are useful for contraception and hormone replacement therapy are described. Also provided are products containing these compounds.

 
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> 2-halogenated derivatives of 5-0 desosaminyl-erythronolide a, their preparation process and their antibiotic use

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