A thermogelling, aliphatically modified polymer for use in drug delivery
is described. Illustrative embodiments include
poly(lactic-co-.epsilon.-caprolactone)-poly(ethylene
glycol)-poly(lactic-co-.epsilon.-caprolactone) hexanoate and
poly(lactic-co-.epsilon.-caprolactone)-poly(ethylene
glycol)-poly(lactic-co-.epsilon.-caprolactone) laurate. Another
illustrative embodiment includes a composition having a thermogelling
amount of an aliphatically modified
poly(lactic-co-.epsilon.-caprolactone)-poly(ethylene
glycol)-poly(lactic-co-.epsilon.-caprolactone) and an effective amount of
a drug. The thermogelling polymers are made by bonding an aliphatic group
to poly(lactic-co-.epsilon.-caprolactone)-poly(ethylene
glycol)-poly(lactic-co-.epsilon.-caprolactone). A method of use includes
injecting a warm-blooded individual with a thermogelling amount of the
aliphatically modified polymer and a drug.