The present invention is directed to controlling plant pest infestation,
and particularly plant nematode infestation, by inhibiting one or more
biological functions in the plant pest. The invention discloses methods
and compositions for use in controlling plant pest infestation by
providing one or more different recombinant double stranded RNA molecules
in the diet of the pest in order to achieve a reduction in pest
infestation through suppression of pest gene expression. The invention is
also directed to methods for making transgenic plants that express the
double stranded RNA molecules, to methods for detecting cells comprising
the disclosed sequences, and to methods for detecting the disclosed
sequences in biological samples.