A foldable intraocular lens (IOL) includes an optic and at least one fixation member for supporting the optic in the anterior chamber of an eye. The fixation member includes an intermediate portion that extends a first direction away from the optic, and a leg portion that intersects with an outer end of the intermediate portion and extends a second direction, different from the first direction, away from the outer end. The leg portion preferably includes a reduced width region near the intersection with the intermediate portion. The reduced width region acts essentially as a hinge allowing the leg portion to flex about the intermediate portion in responsive to compressive forces, while the intermediate portion and optic remain stable.

 
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> Indole-type derivatives as inhibitors of p38 kinase

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