A cutting guide for use in spinal surgery includes a sidewall defining an internal cavity. A chisel guide, for use with the cutting guide, includes a first block member to be inserted into the internal cavity of the cutting guide to position the first block member adjacent the vertebral body. The chisel guide also includes a second block member connected to the first block member. An apparatus for creating a cavity in a vertebral body endplate and in an intervertebral disc may be a compressor or a distractor having at least one cutting implement thereon. A tensioner determines a proper elongation distance in a prosthesis implanted in a vertebral body.

 
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> Method for refolding proteins containing free cysteine residues

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