It is an object of the present invention to provide a nerve growth factor production inhibitor having a function to inhibit the production of the nerve growth factor deeply involved with the extension of C fiber to epidermis, as well as a high safety, and an external preparation for the skin, a cosmetic, a quasi drug, a preventive and remedy for itching and a remedy for atopic dermatitis containing the nerve growth factor production inhibitor. The nerve growth factor production inhibitor is characterized in that an acerola seed extract is combined.