A method for activating an anti-pinch system for a vehicle window regulator, sunroof or driving mechanism includes the steps of starting a motor of the driving mechanism, waiting for a given rotation of the motor and a given time period, and then activating the anti-pinch system. This allows for close monitoring of the behavior of the window regulator when the window regulator is started, and takes account of both the behavior of the drive motor and the behavior of the driving mechanism.