A method and apparatus for treatment of an eating disorder includes
electrically, mechanically and/or pharmaceutically/chemically stimulating
a of the vagus nerve of the lower esophagus, cardia, esophageal/cardia
junction, cardia/fundus junction or upper stomach so as to induce
afferent action potentials on the vagus nerve. The device may be
noninvasively adjusted after implantation to provide increased or
decreased restriction on the patient's gastrointestinal tract. Each
stimulus may be administered as a series of programmed pulses of defined
amplitude, duration and period, to evoke a responsive signal to the brain
by the target nerve, effective for producing a temporary feeling of
satiety in the person. An implantable stimulus generator may be
operatively coupled to a nerve electrode, pressure device or chemical
outlet to apply a defined signal to a selected nerve branch. The
implantable stimulus generator is programmable to allow clinician
programming of defined signal parameters effective to treat the eating
disorder of the patient. Methods are also provided to identify electrodes
nearest to a branch of the vagus nerve to apply an electrical stimulation
signal with improved efficiency.