A system and method for the simulation and modeling of biopharmaceutical batch process manufacturing facilities using process time lines is described herein. The method includes selecting a sequence of unit operations wherein each of the sequence of unit operations has an identifier code. Next, a set of scheduling cycles is selected for each of the sequence of unit operations. A table is then referenced, using the identifier code, to obtain operational parameters for each of the sequence of unit operations. A block flow diagram is then generated using the sequence of unit operations and the operational parameters. A process time line is generated using the operational parameters, the block flow diagram, and the set of scheduling cycles for each of the sequence of unit operations.