A method of installing an ankle prosthesis system provides an artificial talar joint surface and a family of talar stem components having different physical characteristics. Each talar stem component in the family is sized and configured to be attached to the artificial talar joint surface. The method selects an ankle region to be treated and analyzes the morphology of the ankle region. The method selects among the family one of the talar stem components having a desired physical characteristic based upon the analysis. The method forms a prosthesis-receiving cavity that traverses the joint between the talus and a calcaneus and installs the selected one of the talar stem components in the prosthesis-receiving cavity to prevent movement of the joint. The method attaches the artificial talar joint surface to the selected one of the talar stem components.