A composite sheet for delivering therapeutic agents to the skin and method
of use is disclosed. The composite sheet comprises a flexible porous
polymer for holding and releasing the therapeutic agent in a polymer
enrobing material. Micro-channels pass through the polymer enrobing
material and flexible porous polymer to promote the release of the
therapeutic agent. The composite sheet is capable of releasing the
therapeutic agent for periods of up to about 14 to about 30 days.