An Adaptive, Any-Time Case Retrieval process combines existing knowledge (emergent clustering, case retrieval with CRN) in a novel and advantageous way. Although ideally suited to the Digital Body Development System (DBDS), the method is applicable to any problem solving environment involving iterative simulations. Given a description of a problem to be solved, a candidate solution is applied to generate a problem solving base case. The description of the problem is modified and the modification is recorded. Candidate solutions are applied to the problem as modified, thereby generating a problem solving event case. These steps are repeated so as to rank the relevance of the cases generated to arrive at an optimal solution to the problem. In the preferred embodiment a case retrieval network (CRN) structure is used in the ranking process.