An improved aquarium filtration system is provided which includes a bio-reactor chamber. The bio-reactor chamber includes a plurality of bio-balls which have a high surface area for collecting bacteria for biological filtration. The bio-reactor includes one or more pumps for pumping both water and air into the bio-reactor chamber. Preferably, the oxygenated water creates protein laden foam and the bio-reactor chamber includes a removable protein collector. To this end, the bio-reactor chamber includes a vertical column for carrying the protein laden foam into the removable collector.

 
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