A method of assessing a health risk associated with a medication therapy regimen identifies potentially adverse health outcomes resulting from the medication therapy regimen. Methods of assessing a health risk associated with a medication therapy regimen and intervention thereof are provided herein. The methods of assessing a health risk associated with a medication therapy regimen and intervention include receiving information on one or more patient risk factors associated with the person, receiving information on a medical condition, receiving information on a medication being used by the person, evaluating the patient risk factor, the medical condition and medication information to identify an adverse health outcome, and evaluating the likeli.