The present invention provides a method of applying a drug-polymer coating
on a stent. A stent framework is dipped into a first polymeric solution
including a first polymer, a first therapeutic agent, and a first
solvent. The polymeric solution is dried to form a thin drug-polymer
layer on the stent framework. The stent framework with the thin
drug-polymer layer, which is insoluble in the second polymeric solution,
is dipped into a second polymeric solution including a second polymer and
a second solvent and is dried to form a thin barrier layer on the thin
drug-polymer layer. The steps of dipping the stent framework into the
first polymeric solution, drying the first polymeric solution, dipping
the stent framework into the second polymeric solution, and drying the
second polymeric solution are repeated until a target drug-polymer
coating thickness is disposed on the stent framework.