This application relates to a compound of Formula (I) or a
pharmaceutically acceptable salt thereof, pharmaceutical compositions
thereof, and its use as an inhibitor of the NK-1 subtype of tachykinin
receptors, as well as a process for its preparation and intermediates
therefor. (I) wherein: D is a C.sub.1-C.sub.3 alkane-diyl; R.sup.1 is
phenyl, which is optionally substituted with one to three substitutents
independently selected from the group consisting of halo, C.sub.1-C.sub.4
alkyl, C.sub.1-C.sub.4 alkoxy, cyano, difluoromethyl, trifluoromethyl,
and trifluoromethoxy; R.sup.4 is a radical selected from the group
consisting of: (IA), (IB), (IC), (ID), (IE), (IF), (IG), (IH)
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