A sub-harmonic mixer and a down converter with the sub-harmonic mixer are provided. The sub-harmonic mixer includes a differential amplifying unit, a current buffer unit, and a switching unit. The differential amplifying unit is used to amplify a radio frequency (RF) signal and employs a first resonance circuit to force a leakage signal to flow to a first voltage. The current buffer unit is used to amplify the gain of an output signal of the differential amplifying unit and employs a second resonance circuit to force the leakage signal to flow to a second voltage. Finally, the switching unit switches an output signal of the current buffer unit into a base band signal.