System and method for operating a system including one or more co-located computers, e.g., rack-mounted blades, coupled to one or more remote human interfaces (RHIs), and where content or communication is received from sources, e.g., external content sources, internal or external communications sources, etc., and distributed to the RHIs. A first computing system generates first video signals corresponding to a first image for transmission to a display device in a first RHI. The video manager receives a second image from a source, and inserts second video signals corresponding to the second image with the first video signals to form third video signals. The display device of the first RHI displays a third image based on the third video signals, e.g., a picture-in-picture presentation of the second and first images. The first, second, and third video signals may include video streams and/or audio signals, and may be analog, digital, or both.