A method and system for processing synonyms that adapts a general-purpose synonym resource to a specific domain. The method selects out a domain-specific subset of synonyms from the set of general-purpose synonyms. The synonym processing method in turn comprises two methods that can be used either together or on their own. A method of synonym pruning eliminates those synonyms that are inappropriate in a specific domain. A method of synonym optimization eliminates those synonyms that are unlikely to be used in a specific domain. The method has many applications including, but not limited to, information retrieval and domain-specific thesauri as a writer's aid.