Methods and apparatus for synchronizing Wireless Local Area Network (WLAN) communication within a multi-mode radio. A multi-mode radio can support communication with a WLAN and at least one other wireless communication system. The multiple systems can be distinct and asynchronous. Transmitting, or attempting to transmit, over a WLAN communication link can result in interference that degrades the sensitivity of a receiver in another communication system, or that interferes with a transmission in another communication system. The WLAN transmissions can be synchronized to operation in another communication system by generating a signal that can be coupled to a collision avoidance system in the WLAN transmitter. The signal can operate to cause the WLAN transmitter to reschedule the transmission to another time such that the resources of the multi-mode radio are conserved and the WLAN interference is minimized.