The invention relates to pyrazolopyrimidine derivatives of formula (I)
wherein Y.sup.1, Y.sup.2 and Y.sup.3 independently are e.g. CR.sup.10,
NH, S or O, whereby at least one of Y.sup.1, Y.sup.2 and Y.sup.3
represents CR.sup.10; R.sup.1 represents chloro or bromo; R.sup.2,
R.sup.3, R.sup.4, R.sup.5, R.sup.6 and R.sup.7 represent e.g. hydrogen or
C.sub.1-C.sub.6-alkyl, and R.sup.10 represents e.g. hydrogen, halogen or
phenyl; which are potent mGluR5 modulators and are e.g. useful for the
treatment of various neurological disorders.