A series of new
4,6-diamino-1,2-dihydro-1-aryl-2-(-tricyclo[3.3.1.1.sup.3,7]decyl]-1,3,5--
triazines where the aryl group is a substituted or unsubstituted phenyl,
or naphthyl-group, as pharmaceutically accepted salts or as free bases.
The phenyl group substituents are halides, alkyls, alkoxyls or nitro
group. One or more of the above substituents are found one or more times
each one, and in various positions of the phenyl group. The corresponding
isomers, stereoisomers, enantiomers, free bases and their complexes with
various natural macromolecules and synthetic derivatives of them. The
invention refers to new and prototype compounds inhibiting the
proliferation of unwanted cells that belong to pathogenic microorganisms,
to human tissues, to pathological cells, or any pathological cell
proliferation. It also refers to the synthesis and the method of
synthesis of the above mentioned compounds. The synthesis and the method
of synthesis thereof of a series characterized by the preparation of the
final triazines, by cyclization of the bigouanide hydrochlorides with
adamantane-1-carboxaldehyde. Preparation of the inclusion complexes is
realized from compexation of the corresponding hydrochlorides of the
above mentioned triazines with natural macromolecules or synthetic
derivatives.