A multi-layer dental panoramic and transverse x-ray imaging system includes an x-ray source; a digital imaging device capable of frame mode output with a sufficient frame rate; a mechanical manipulator having at least one rotational axis located in a position other than the focal point of the x-ray source; a position detection mechanism for detecting the camera position in 1D, 2D or 3D depending of the complexity of the trajectory; a final image reconstruction mechanism for reconstructing the final images out of the stored frames; a real time storage system such as RAM, hard drive or an drive array able to store all the frames captured during an exposure; and a digital processing unit capable of executing the reconstruction algorithm, such components being interconnected in operational arrangement. The system produces selectively dental panoramic x-ray images, dental transverse x-ray images and dental tomosynthetic 3D images from a frame stream produced by a high-speed, x-ray digital imaging device.