A product of vegetal origin with a high percentage of proanthocyanidines with molecular weight of greater than 6000 daltons, a very high percentage of which proanthocyanidines have a molecular weight of greater than 30000 daltons, produces a great hypercholesterolaernic effect at acceptable doses for human consumption and little astringent and anti-nutritional effects. The product of vegetal origin may be presented as medicine, pharmaceutical composition, dietary complement or food product. An industrial process is provided for preparation of the product from dicotyledons.