This invention relates to a peptide or protein capable of converting a
transcription factor into a transcriptional repressor, a gene encoding
such peptide or protein, a chimeric protein in which the aforementioned
peptide or protein is fused to a transcription factor, a chimeric gene in
which the gene encoding a peptide or protein is fused to a gene encoding
a transcription factor, a recombinant vector having such chimeric gene,
and a transformant comprising such recombinant vector. The peptide of the
invention that is capable of converting a transcription factor into a
transcriptional repressor is very short. Thus, it can be very easily
synthesized, and it can effectively and selectively repress the
transcription of a specific gene. Accordingly, such gene is applicable to
and useful in a wide variety of fields, such as repression of the
expression of cancerous genes and regulation of the expression of genes
encoding pigment-metabolic enzymes.