An x-ray system quick-connect connection is disclosed to allow an end-user to de-couple a portable x-ray detector from an x-ray scanner/host. The quick-connect connection is accessible by the end-user without removal of a service panel that exposes an interior service portion of the x-ray scanner or x-ray detector. The de-coupled x-ray detector may be stored independently from the x-ray scanner/host and may be shared among multiple x-ray scanner/host systems, when properly calibrated. De-coupling a single quick-connect connection de-couples all power and communication lines between the x-ray scanner/host and the x-ray detector.