A compound represented by the general formula (1):
Q.sup.1-Q.sup.2-T.sup.0-N(R.sup.1)-Q.sup.3-N(R.sup.2)-T.sup.1-Q.sup.4
(1) wherein R.sup.1 and R.sup.2 are hydrogen atoms or the like; Q.sup.1
is a saturated or unsaturated, 5- or 6-membered cyclic hydrocarbon group
which may be substituted, or the like; Q.sup.2 is a single bond or the
like; Q.sup.3 is a group ##STR00001## in which Q.sup.5 is an alkylene
group having 1 to 8 carbon atoms, or the like; and T.sup.0 and T.sup.1
are carbonyl groups or the like; a salt thereof, a solvate thereof, or an
N-oxide thereof.The compound is useful as an agent for preventing and/or
treating cerebral infarction, cerebral embolism, myocardial infarction,
angina pectoris, pulmonary infarction, pulmonary embolism, Buerger's
disease, deep venous thrombosis, disseminated intravascular coagulation
syndrome, thrombus formation after valve or joint replacement, thrombus
formation and reocclusion after angioplasty, systemic inflammatory
response syndrome (SIRS), multiple organ dysfunction syndrome (MODS),
thrombus formation during extracorporeal circulation, or blood clotting
upon blood drawing.