Tumor vaccines for the use against MUC1 positive carcinomas are presented.
A tumor vaccine containing synthetic peptides comprising sequences of the
human epithelial mucin MUC1 containing the immunodominat region PDTRPAP
which is glycosylated at the threonine. Preferred glycosylation of the
immunodominant region is a O-glycosidically linked
a-N-acetylgalactosamine (GalNAc) or short chained oligosaccharides. The
present invention can be used on all MUC1-positive carcinomas.