The invention relates to a novel process for the preparation of an
aminoalcohol of the formula ##STR00001## racemically or optically
active, starting from 2-azabicyclo[2.2.1]hept-5-en-3-one, its further
conversion to give the corresponding acyl derivative and its further
conversion to (1S,4R)- or
(1R,4S)-4-(2-amino-6-chloro-9-H-purine-9-yl)-2-cyclopentenyl-1-methanol
of the formulae ##STR00002## In the latter synthesis, the aminoalcohol
is converted into the corresponding D- or L-tartrate, which is then
reacted with N-(2-amino-4,6-dichloropyrimidin-5-yl)formamide of the
formula ##STR00003## to give (1S,4R)- or
(1R,4S)-4-[(2-amino-6-chloro-5-formamido-4-pyrimidinyl)amino]-2-cyclopent-
enyl-1-methanol of the formulae ##STR00004## and then cyclized to give
the end compounds.