This invention contemplates improved methods of enzymatic production of
carbohydrates especially fucosylated carbohydrates. Improved syntheses of
glycosyl 1- or 2-phosphates using both chemical and enzymatic means are
also contemplated. The phosphorylated glycosides are then used to produce
sugar nucleotides that are in turn used as donor sugars for glycosylation
of acceptor carbohydrates. Especially preferred herein is the use of a
disclosed method for fucosylation.