Described herein are compounds that are useful as protein kinase inhibitors having the formula: ##STR00001## wherein A.sup.1, A.sup.2, T.sub.mR.sup.1, X, R.sup.2, R.sup.3, R.sup.9, R.sup.12, and R.sup.13 are as described in the specification. The compounds are especially useful as inhibitors of ERK2, Aurora2, GSK3, CDK2, AKT3, and ROCK protein kinases and for treating diseases in mammals that are alleviated by a protein kinase inhibitor, particularly diseases such as cancer, neurodegenerative disorders, inflammatory disorders, restenosis, diabetes, and cardiovascular disease.

 
Web www.patentalert.com

< Methods for genetic modification of hematopoietic progenitor cells and uses of the modified cells

> Substituted acylhydroxamic acids and method of reducing TNF.alpha.levels

~ 00419