The invention relates to 5,6-diphenylpyridine-3-carboxamide derivatives of general formula (I): ##STR00001## where: R.sub.1 represents hydrogen or a (C.sub.1-C.sub.4)alkyl; R.sub.2 represents: a monoazo saturated heterocycle of 5 to 7 atoms, the nitrogen atom being substituted with a (C.sub.1-C.sub.4)alkanoyl; NR.sub.10R.sub.11; a nonaromatic (C.sub.3-C.sub.10) carbocycle more than tri-substituted with (C.sub.1-C.sub.4)alkyl; a nonaromatic (C.sub.11-C.sub.12) carbocycle unsubstituted or mono- or polysubstituted with (C.sub.1-C.sub.4)alkyl; a monooxygenated saturated heterocycle with 5 to 7 atoms, more than tri-substituted with (C.sub.1-C.sub.4)alkyl; or R.sub.1 and R.sub.2, together with the nitrogen atom to which the above are bonded, form a 4-disubstituted piperidin-1-yl group; the salts, solvates and hydrates thereof. The invention further relates to a method for production and therapeutic application thereof.