This invention provides compounds having drug and bio-affecting properties, their pharmaceutical compositions and method of use. In particular, the invention is concerned with new piperidine 4-alkenyl derivatives that possess unique antiviral activity. More particularly, the present invention relates to compounds useful for the treatment of HIV and AIDS. The compounds of the invention for the general Formula I: ##STR00001## wherein: Z is ##STR00002## Q is selected from the group consisting of: ##STR00003## --W-- is ##STR00004##