An organic electro luminescence device is provided. A thin film transistor (TFT) is formed within a sub-pixel region defined by a gate line and a data line on a substrate. A passivation layer and a first electrode are sequentially formed on the substrate where the TFT is formed. A contact hole is formed at a predetermined portion of the passivation layer and the first electrode so as to expose a drain electrode of the TFT. An electrode separator and a buffer layer are misaligned with the gate line by a predetermined position, such that an emission region corresponding to the sub-pixel and a region including the contact hole of the TFT are separated. An organic electro luminescent layer is formed within a region defined by the buffer region. A second electrode is formed on the organic electrode luminescent layer and is connected to the drain electrode of the TFT through the contact hole.