A system and method for generation of efficient calls from compiled byte code within a virtual machine (VM) or Java Virtual Machine (JVM) environment. Current techniques used to interface dynamically compiled byte code with native libraries using stubs are unsatisfactory due to non-optimal performance and the large amount of manual work needed to maintain the stub generation code. An embodiment of the present invention addresses this by providing a system and a method for automatic stub generation based on a small set of parameters stored in a ParamInfo structure. In accordance with an embodiment, the system comprises a computer with native libraries; a virtual machine for executing a software application; a memory space for the compiled byte code; and a compiler with a calling convention adaptor that integrates native calls into the high level analysis step of the compilation of byte codes, so that the overhead for the native call is reduced.