Methods, apparatuses, computer program products, devices and systems are described that accepting an input identifying at least one treatment target in search of an agent; accessing at least one dataset containing at least one agent for use in the context of the at least one treatment target; applying at least one filter criterion to tile at least one dataset to identify a subset of the at least one dataset, the subset of tile at least one dataset associated with a defined level of at least one adverse event associated with administration of the at least one agent: and presenting the at least one agent in response to the subset of the at least one dataset.