Short peptides are provided, which bind to a body fluid sample obtained
from a schizophrenic patient at a substantively higher level than to a
body fluid sample obtained from a non-schizophrenic individual. The
peptides are no more than 10 amino acids long and comprise a continuous
sequence of at least 5 amino acids which consists of at least one
positively charged amino acid at one of its ends. The provided peptides,
which are the putative binding sites of autoantibodies found in high
levels in schizophrenic individuals, are thus useful in diagnosis of
schizophrenia.